Indel
Indel
Indel (/ɪnˈdɛl/) is a term used in genetics to refer to the insertion or deletion of bases in the DNA sequence of an organism's genome. The term "indel" is a portmanteau of the words "insertion" and "deletion".
Etymology
The term "indel" was coined by combining the words "insertion" and "deletion". It was first used in the late 20th century as geneticists began to discover the impact of these mutations on genetic diversity and disease.
Definition
An indel is a type of mutation where an extra base pair is inserted into a DNA sequence or a base pair is deleted from a DNA sequence. This can lead to a frameshift mutation if the number of base pairs inserted or deleted is not a multiple of three, as the genetic code is read in groups of three base pairs, known as codons.
Related Terms
- Frameshift mutation: A type of mutation caused by indels.
- Codon: A sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis.
- Genome: The complete set of genes or genetic material present in a cell or organism.
- Genetics: The study of genes, genetic variation, and heredity in living organisms.
- DNA: Deoxyribonucleic acid, a self-replicating material which is present in nearly all living organisms as the main constituent of chromosomes. It is the carrier of genetic information.
External links
- Medical encyclopedia article on Indel
- Wikipedia's article - Indel
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski