- 1 Information about Indinavir
- 2 Liver safety of Indinavir
- 3 Mechanism of action of Indinavir
- 4 FDA approval information for Indinavir
- 5 Dosage and administration for Indinavir
- 6 Side effects of Indinavir
- 7 Antiviral agents
- 8 Cost and Coupons - Indinavir
- 9 Reviews for Indinavir
- 10 Articles on Indinavir
- 11 Learn more about Indinavir
- 12 Help WikiMD
Indinavir can cause transient and usually asymptomatic elevations in serum aminotransferase levels and mild elevations in indirect bilirubin concentration. Indinavir is a rare cause of clinically apparent, acute liver injury. In HBV or HCV coinfected patients, antiretroviral therapy with indinavir may result in an exacerbation of the underlying chronic hepatitis B or C.
Indinavir (in din' a vir) is an antiretroviral protease inhibitor that acts by binding to the catalytic site of the HIV protease, thereby preventing the cleavage of viral polyprotein precursors into mature, functional proteins that are necessary for viral replication.
Indinavir was approved for use in the United States in 1996 and continues to be commonly used in combination with other antiretroviral agents for the treatment of HIV infection. Indinavir is available under the brand name Crixivan in capsules of 100, 200 and 400 mg. Indinavir is typically used in combination with a low dose of ritonavir, which improves its pharmacokinetics.
The recommended dosage of indinavir is 800 mg orally every 8 hours with or without ritonavir (usually 100 to 200 mg twice daily).
Drugs for HIV Infection, in the Subclass Antiretroviral Agents
- Nonnucleoside Reverse Transcriptase Inhibitors (HIV)
- Nucleoside Analogues (HIV)
- Protease Inhibitors (HIV)
HCV NS5A Inhibitors
HCV NS5B (Polymerase) Inhibitors
- Asunaprevir, Boceprevir, Glecaprevir, Grazoprevir, Paritaprevir, Simeprevir, Telaprevir, Voxilaprevir
Drugs for Herpes Virus Infections (HSV, CMV, others)
Drugs for Influenza
- GoodRx compare cost & coupons for Indinavir
- Find the lowest cost of Indinavir
- Search for Coupons for Indinavir
Find something you can improve? Join WikiMD as an an editor and help improve this page or others.