Inosine monophosphate
Inosine Monophosphate
Inosine monophosphate (IMP), also known as inosinic acid (pronunciation: /ɪˈnoʊsɪn/ /ˈmɒnəˌfɒsfeɪt/), is a type of nucleotide that is important in metabolism. It is a purine nucleotide which is present in all living cells and plays a crucial role in energy transfer and DNA and RNA synthesis.
Etymology
The term "Inosine monophosphate" is derived from the Greek word "inos", meaning sinew or muscle, and the Latin word "monophosphas", meaning single phosphate.
Structure and Function
Inosine monophosphate is composed of the nucleoside inosine and one phosphate group. It is an intermediate in the purine metabolism pathway, where it is synthesized from adenosine monophosphate (AMP) and guanosine monophosphate (GMP). It can also be converted back into these nucleotides, providing flexibility in the regulation of nucleotide synthesis.
Clinical Significance
Inosine monophosphate has been studied for its potential therapeutic uses. For example, it has been suggested that it may be useful in the treatment of Parkinson's disease and multiple sclerosis. However, more research is needed to confirm these findings.
Related Terms
- Nucleotide
- Metabolism
- Purine nucleotide
- Energy transfer
- DNA
- RNA
- Nucleoside
- Purine metabolism
- Adenosine monophosphate
- Guanosine monophosphate
- Parkinson's disease
- Multiple sclerosis
External links
- Medical encyclopedia article on Inosine monophosphate
- Wikipedia's article - Inosine monophosphate
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