Insertion sequence
Insertion Sequence
Insertion sequence (pronunciation: in-sert-shun se-kwens) is a type of transposable element that carries only the genetic information necessary for its own transposition.
Etymology
The term "Insertion sequence" originates from the process of its function. It "inserts" itself into new locations within the genome, hence the name.
Definition
An Insertion sequence is a short DNA sequence that acts as a simple transposable element. They are capable of moving from one location in the genome to another and are typically composed of a transposase gene flanked by inverted repeat sequences. The transposase enzyme recognizes the inverted repeats and catalyzes the reaction to move the sequence to a new location.
Related Terms
- Transposable element: A DNA sequence that can change its position within the genome, creating or reversing mutations and altering the cell's genetic identity and genome size.
- Transposase: An enzyme that binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome.
- Inverted repeat sequences: Sequences of DNA that are the reverse complement of each other.
- Genome: The complete set of genes or genetic material present in a cell or organism.
See Also
External links
- Medical encyclopedia article on Insertion sequence
- Wikipedia's article - Insertion sequence
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