Ipilimumab

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Ipilimumab
TermIpilimumab
Short definitionipilimumab (ih-pih-LIH-myoo-mab) A drug that binds to the protein CTLA-4 to help immune cells kill cancer cells better, and is used to treat many different types types of cancer is used. These include cancers that have certain mutations (changes) in genes involved in DNA repair. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


ipilimumab - (pronounced) (ih-pih-LIH-myoo-mab) A drug that binds to the protein CTLA-4 to help immune cells kill cancer cells better, and is used to treat many different types types of cancer is used. These include cancers that have certain mutations (changes) in genes involved in DNA repair. Ipilimumab is used alone or with other medicines to treat certain types of colon cancer, esophageal cancer, hepatocellular carcinoma (a type of liver cancer), malignant pleural mesothelioma, melanoma, non-small cell lung cancer, and renal cell carcinoma (a type of kidney cancer). It is also being studied in the treatment of other types of cancer. Ipilimumab can block CTLA-4 and help the immune system kill cancer cells. It's a type of monoclonal antibody and a type of immune checkpoint inhibitor. Also called MDX-010 and Yervoy

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