- 1 Information about Itraconazole
- 2 Liver safety of Itraconazole
- 3 Mechanism of action of Itraconazole
- 4 Clinical use of Itraconazole
- 5 FDA approval information for Itraconazole
- 6 Dosage and administration for Itraconazole
- 7 Side effects of Itraconazole
- 8 Cost and Coupons - Itraconazole
- 9 Reviews for Itraconazole
- 10 Articles on Itraconazole
- 11 Learn more about Itraconazole
- 12 Help WikiMD
Information about Itraconazole
Itraconazole is a orally administered, triazole antifungal agent used in the treatment of systemic and superficial fungal infections.
Liver safety of Itraconazole
Itraconazole therapy is associated with transient, mild-to-moderate serum elevations and can lead to clinically apparent acute drug induced liver injury.
Mechanism of action of Itraconazole
Itraconazole (it" ra kon' a zole) is a synthetic triazole fungicidal agent which acts by inhibition of fungal C14-a- ergosterol demethylase, which leads to a decrease in ergosterol synthesis, a necessary component of fungal cell membranes.
Clinical use of Itraconazole
FDA approval information for Itraconazole
Itraconazole was approved for use in the United States in 1992 and continues to be widely used as an antifungal agent.
Dosage and administration for Itraconazole
Current indications include blastomycosis, histoplasmosis, aspergillosis and onychomycosis. Itraconazole is available in capsules of 100 mg, tablets of 200 mg and oral suspensions of 10 mg/mL in generic forms and under the brand name Sporanox. The typical dose is 100 to 400 mg daily based upon the type and severity of the fungal infection.
Side effects of Itraconazole
The following drugs are antifungal agents:
- Amphotericin B
Cost and Coupons - Itraconazole
Reviews for Itraconazole
Articles on Itraconazole
Learn more about Itraconazole
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