Joffroy's sign
Joffroy's Sign
Joffroy's Sign (/ʒɔːfˈrɔɪz saɪn/) is a clinical sign often used in the diagnosis of Graves' disease, a common form of hyperthyroidism. It is named after the French neurologist Alexis Joffroy who first described it in the late 19th century.
Etymology
The term "Joffroy's Sign" is derived from the name of its discoverer, Alexis Joffroy, a French neurologist who made significant contributions to the field of neurology in the late 19th and early 20th centuries.
Definition
Joffroy's Sign is defined as the absence of forehead wrinkles when a patient looks upward with the head bent forward. This is due to the overactivity of the levator palpebrae superioris muscle, which is innervated by the oculomotor nerve (cranial nerve III). This overactivity is a characteristic feature of Graves' disease.
Related Terms
- Graves' disease: An autoimmune disorder that results in the overproduction of thyroid hormones, or hyperthyroidism.
- Hyperthyroidism: A condition in which the thyroid gland produces too much thyroid hormone.
- Levator palpebrae superioris: The muscle in the upper part of the eyelid that raises the eyelid.
- Oculomotor nerve: The third cranial nerve, which controls most of the eye movements and pupil constriction.
See Also
External links
- Medical encyclopedia article on Joffroy's sign
- Wikipedia's article - Joffroy's sign
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