Kindling model
Kindling Model
The Kindling Model (pronunciation: /ˈkɪndlɪŋ mɒdəl/) is a scientific model used in the field of neuroscience to explain the phenomenon of sensitization to stimuli, particularly in relation to epilepsy and other neurological disorders.
Etymology
The term "kindling" is derived from the English word "kindle", which means to ignite or set on fire. This is a metaphorical representation of the process in the brain where repeated exposure to a stimulus can lead to an enhanced response.
Definition
The Kindling Model is a process where repeated, low-intensity stimulation of certain brain areas can lead to the development of seizures. This model is often used in research to understand the development and progression of epilepsy. The kindling effect can be produced by a variety of stimuli, including electrical currents and certain chemicals.
Related Terms
- Neuroplasticity: The ability of the brain to change and adapt in response to experience.
- Long-term potentiation: A long-lasting enhancement in signal transmission between two neurons that results from stimulating them simultaneously.
- Epileptogenesis: The process by which a normal brain develops epilepsy.
Application
The Kindling Model has been used extensively in research to understand the mechanisms underlying the development of epilepsy. It has also been used to test the effectiveness of anti-epileptic drugs. The model has been instrumental in demonstrating that the brain's response to certain stimuli can change over time, leading to the development of seizures.
See Also
External links
- Medical encyclopedia article on Kindling model
- Wikipedia's article - Kindling model
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