Kolliphor EL

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Kolliphor EL

Kolliphor EL (pronunciation: /ˈkɒlɪfɔːr ˈiː ˈɛl/), also known as Polyoxyl 35 Castor Oil, is a non-ionic surfactant and solubilizer used in the pharmaceutical industry.

Etymology

The term "Kolliphor" is derived from the Greek words "kólli" meaning glue and "phorós" meaning bearing. "EL" stands for "Emulsifying Liquid". The name signifies its primary function as a carrier of active pharmaceutical ingredients.

Usage

Kolliphor EL is used in the formulation of intravenous and parenteral drugs, particularly those that are poorly soluble. It is also used in the production of emulsions and nanoparticles.

Related Terms

  • Surfactant: A substance that reduces the surface tension of a liquid, allowing it to spread more easily.
  • Solubilizer: A substance that can increase the solubility of another substance.
  • Intravenous: Administered into a vein.
  • Parenteral: Administered in a manner other than through the digestive tract, typically by injection.
  • Emulsion: A mixture of two or more liquids that are normally immiscible.
  • Nanoparticle: A microscopic particle with at least one dimension less than 100 nanometers.

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