Landau-Kleffner Syndrome
Landau-Kleffner Syndrome (pronounced LAN-dow KLEF-ner sin-drome) is a rare, childhood neurological disorder characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electro-encephalogram (EEG). The syndrome is also known as infantile acquired aphasia, acquired epileptic aphasia or aphasia with convulsive disorder. This disorder usually occurs in children between the ages of 3 and 7 years.
Etymology
The syndrome is named after Dr. William M. Landau and Dr. Frank R. Kleffner, who first reported on six cases in 1957.
Symptoms
Children with Landau-Kleffner Syndrome typically develop normally but then lose their language skills for no apparent reason. While some children may have seizures, others may only have abnormal EEGs without having noticeable seizures. Some children may also develop behavioral and social problems.
Causes
The exact cause of Landau-Kleffner Syndrome is unknown. However, it is believed to be caused by abnormal electrical activity in the brain, which is often associated with seizures. Some researchers believe that it may be an autoimmune disorder.
Diagnosis
Diagnosis of Landau-Kleffner Syndrome is based on the presence of its characteristic symptoms, a detailed patient history, a thorough clinical evaluation, and a variety of specialized tests, including an EEG.
Treatment
Treatment for Landau-Kleffner Syndrome is symptomatic and supportive. It often involves a combination of medications, speech therapy, and educational support. In some cases, surgery may be recommended.
Prognosis
The prognosis for children with Landau-Kleffner Syndrome varies. Some children may regain much of their language ability, while others may continue to have language difficulties.
See also
External links
- Medical encyclopedia article on Landau-Kleffner Syndrome
- Wikipedia's article - Landau-Kleffner Syndrome
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