Lerisetron
Lerisetron
Lerisetron (pronounced: leh-RIH-seh-tron) is a potent and selective 5-HT3 receptor antagonist used in the management of chemotherapy-induced nausea and vomiting (CINV). It is not currently available in the United States.
Etymology
The name "Lerisetron" is derived from its chemical structure: 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxamide.
Pharmacology
Lerisetron works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. It is a potent and selective antagonist of the 5-HT3 receptor, a type of serotonin receptor found primarily in the brain and in the gastrointestinal tract.
Related Terms
- 5-HT3 receptor antagonist: A class of medications that are primarily used to treat and prevent chemotherapy-induced nausea and vomiting.
- Chemotherapy: A type of cancer treatment that uses drugs to destroy cancer cells.
- Nausea: An unpleasant, diffuse sensation of unease and discomfort, often perceived as an urge to vomit.
- Vomiting: The involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
- Serotonin: A neurotransmitter that sends signals between your nerve cells.
See Also
External links
- Medical encyclopedia article on Lerisetron
- Wikipedia's article - Lerisetron
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