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Lestaurtinib

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Lestaurtinib
Lestaurtinib.png
Clinical data
ATC code
  • none
Identifiers
PubChem CID
UNII
KEGG
ChEMBL
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC26H21N3O4
Molar mass439.462 g/mol g·mol−1
 ☒NcheckY (what is this?)  (verify)

Lestaurtinib (rINN, codenamed CEP-701) is a tyrosine kinase inhibitor structurally related to staurosporine, and is being developed by Cephalon.

It is an inhibitor of FLT3,[1] JAK2,[2] TrkA, TrkB and TrkC.[3]

Uses

It is undergoing research for the treatment of acute myelogenous leukemia (AML) and myeloproliferative disorders.

As of 2009, it is in Phase II clinical trials for AML and Phase II clinical trials for myeloproliferative disorders.[4][5]

See also

References


 

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