Locus heterogeneity
Locus heterogeneity | |
---|---|
Term | Locus heterogeneity |
Short definition | locus heterogeneity (LOH-kus HEH-teh-roh-jeh-NEE-ih-tee) A term used to describe when mutations (changes) in different genes cause the same disease or condition cause. Any mutation alone is sufficient to cause the disease or condition. |
Type | Cancer terms |
Specialty | Oncology |
Language | English |
Source | NCI |
Comments |
locus heterogeneity - (pronounced) (LOH-kus HEH-teh-roh-jeh-NEE-ih-tee) A term used to describe when mutations (changes) in different genes cause the same disease or condition cause. Any mutation alone is sufficient to cause the disease or condition. For example, xeroderma pigmentosum (a rare, inherited condition with a very high risk of skin and other cancers) is caused by a mutation in one of at least nine different genes involved in repairing damaged DNA
External links
- Medical encyclopedia article on Locus heterogeneity
- Wikipedia's article - Locus heterogeneity
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