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Low-carbohydrate diets or carbohydrate-restricted diets (CRDs) are diets that restrict carbohydrate consumption relative to the average diet. Foods high in carbohydrates (e.g., sugar, bread, pasta) are limited, and replaced with foods containing a higher percentage of fat and protein (e.g., meat, poultry, fish, shellfish, eggs, cheese, nuts, and seeds), as well as low carbohydrate foods (e.g. spinach, kale, chard, collards, and other fibrous vegetables).
There is a lack of standardization of how much carbohydrate low-carbohydrate diets must have, and this has complicated research. One definition, from the American Academy of Family Physicians, specifies low-carbohydrate diets as having less than 20% carbohydrate content.
Low-carbohydrate diets are associated with increased mortality, and they can miss out on the health benefits afforded by high-quality carbohydrate such as is found in legumes including grain legumes or pulses, and fruit and vegetables. Disadvantages of the diet might include halitosis, headache and constipation, and in general the potential adverse effects of the diet are under-researched, particularly for more serious possible risks such as for bone health and cancer incidence.
Carbohydrate-restricted diets can be as effective, or marginally more effective, than low-fat diets in helping achieve weight loss in the short term. In the long term, effective weight maintenance depends on calorie restriction, not the ratio of macronutrients in a diet. The hypothesis proposed by diet advocates that carbohydrate causes undue fat accumulation via the medium of insulin, and that low-carbohydrate diets have a "metabolic advantage", has been falsified by experiment.
It is not clear how low-carbohydrate dieting affects cardiovascular health; any benefit from HDL cholesterol might be offset by raised LDL cholesterol, which risks causing clogged arteries in the long term.
Carbohydrate-restricted diets are no more effective than a conventional healthy diet in preventing the onset of type 2 diabetes, but for people with type 2 diabetes they are a viable option for losing weight or helping with glycemic control. There is little evidence that low-carbohydrate dieting is helpful in managing type 1 diabetes. The American Diabetes Association recommends that people with diabetes should adopt a generally healthy diet, rather than a diet focused on carbohydrate or other macronutrients.
An extreme form of low-carbohydrate diet – the ketogenic diet – is established as a medical diet for treating epilepsy. Through celebrity endorsement it has become a popular weight-loss fad diet, but there is no evidence of any distinctive benefit for this purpose, and it may have a number of initial side effects. The British Dietetic Association named it one of the "top 5 worst celeb diets to avoid in 2018".
- 1 Definition and classification
- 2 Adoption and advocacy
- 3 Health aspects
- 4 History
- 5 See also
- 6 References
Definition and classification
The macronutrient ratios of low-carbohydrate diets are not standardized. Template:Asof the conflicting definitions of "low-carbohydrate" diets have complicated research into the subject.
The American Academy of Family Physicians defines low-carbohydrate diets as diets that restrict carbohydrate intake to 20 to 60 grams per day, typically less than 20% of caloric intake. A 2016 review of low-carbohydrate diets classified diets with 50g of carbohydrate per day (less than 10% of total calories) as "very low" and diets with 40% of calories from carbohydrates as "mild" low-carbohydrate diets. The optimal proportion of carbohydrate in a diet for health is thought to be 50-55%.
There is evidence that the quality, rather than the quantity, of carbohydrate in a diet is important for health, and that high-fiber slow-digesting carbohydrate-rich foods are healthful while highly-refined and sugary foods are less so. People choosing diet for health conditions should have their diet tailored to their individual requirements. For people with metabolic conditions, a diet with approximately 40-50% carbohydrate is recommended.
Most vegetables are low- or moderate-carbohydrate foods (in some low-carbohydrate diets, fiber is excluded because it is not a nutritive carbohydrate). Some vegetables, such as potatoes, carrots, maize (corn) and rice are high in starch. Most low-carbohydrate diet plans accommodate vegetables such as broccoli, spinach, kale, lettuce, cucumbers, cauliflower, peppers and most green-leafy vegetables.
Adoption and advocacy
The National Academy of Medicine recommends a minimum intake of 130 g of carbohydrate per day. The FAO and WHO similarly recommend that the majority of dietary energy come from carbohydrates. Low-carbohydrate diets are not an option recommended in the 2015-2020 edition of Dietary Guidelines for Americans, which instead recommends a low fat diet.
Carbohydrate has been wrongly accused of being a uniquely "fattening" macronutrient, misleading many dieters into compromising the nutritiousness of their diet by eliminating carbohydrate-rich food. Low-carbohydrate diet proponents emphasize research saying that low-carbohydrate diets can initially cause slightly greater weight loss than a balanced diet, but some studies suggest that such an advantage does not persist. In the long-term successful weight maintenance is determined by calorie intake, and not by macronutrient ratios.
The public has become confused by the way in which some diets, such as the Zone diet and the South Beach diet are promoted as "low-carbohydrate" when in fact they would more properly be termed "medium" carbohydrate diets.
Low-carbohydrate diet advocates including Gary Taubes and David Ludwig have proposed a "carbohydrate-insulin hypothesis" in which carbohydrate is said to be uniquely fattening because it raises insulin levels and so causes fat to accumulate unduly. The hypothesis appears to run counter to known human biology whereby there is no good evidence of any such association between the actions of insulin and fat accumulation and obesity. The hypothesis predicted that low-carbohydrate dieting would offer a "metabolic advantage" of increased energy expenditure equivalent to 400-600 kcal/day, in accord with the promise of the Atkin's diet: a "high calorie way to stay thin forever".
With funding from the Laura and John Arnold Foundation, in 2012 Taubes co-founded the Nutrition Science Initiative (NuSI), with the aim of raising over $200 million to undertake a "Manhattan Project for nutrition" and validate the hypothesis. Intermediate results, published in the American Journal of Clinical Nutrition did not provide convincing evidence of any advantage to a low-carbohydrate diet as compared to diets of other composition – ultimately a very low-calorie, ketogenic diet (of 5% carbohydrate) "was not associated with significant loss of fat mass" compared to a non-specialized diet with the same calories; there was no useful "metabolic advantage". In 2017 Kevin Hall, a NIH researcher hired to assist with the project, wrote that the carbohydrate-insulin hypothesis had been falsified by experiment. Hall wrote "the rise in obesity prevalence may be primarily due to increased consumption of refined carbohydrates, but the mechanisms are likely to be quite different from those proposed by the carbohydrate–insulin model".
It has been repeatedly found that in the long-term, all diets with the same calorific value perform the same for weight loss, except for the one differentiating factor of how well people can faithfully follow the dietary programme. A study comparing groups taking low-fat, low-carbohydrate and Mediterranean diets found at six months the low-carbohydrate diet still had most people adhering to it, but thereafter the situation reversed: at two years the low-carbohydrate group had the highest incidence of lapses and dropouts. This may be due to the comparatively limited food choice of low-carbohydrate diets.
Studies have shown that people losing weight with a low-carbohydrate diet, compared to a low-fat diet, have very slightly more weight loss initially, equivalent to approximately 100kcal/day, but that the advantage diminishes over time and is ultimately insignificant. The Endocrine Society state that "when calorie intake is held constant [...] body-fat accumulation does not appear to be affected by even very pronounced changes in the amount of fat vs carbohydrate in the diet."
Much of the research into low-carbohydrate dieting has been of poor quality and studies which reported large effects have garnered disproportionate attention in comparison to those which are methodologically sound. Higher quality studies tend to find no meaningful difference in outcome between low-fat and low-carbohydrate dieting. Low-quality meta-analyses have tended to report favourably on the effect of low-carbohydrate diets: a systematic review found that 9 out of 10 meta-analyses with positive conclusions were affected by publication bias.
Template:Asof it was unclear whether low-carbohydrate dieting had any beneficial effect on cardiovascular health, though such diets can cause high LDL cholesterol levels, which carry a risk of atherosclerosis in the long term. Potential favorable changes in triglyceride and HDL cholesterol values should be weighed against potential unfavorable changes in LDL and total cholesterol values.
Some randomized control trials have shown that low-carbohydrate diets, especially very low-carbohydrate diets, perform better than low-fat diets in improving cardiometabolic risk factors in the long term, suggesting that low-carbohydrate diets are a viable option alongside low-fat diets for people at risk of cardiovascular disease.
There is only poor-quality evidence of the effect of different diets on reducing or preventing high blood pressure, but it suggests the low-carbohydrate diet is among the better-performing ones, while the DASH diet performs best.
There is little evidence for the effectiveness of low-carbohydrate diets for people with type 1 diabetes. For certain individuals, it may be feasible to follow a low-carbohydrate regime combined with carefully-managed insulin dosing, this can be hard to maintain and there are concerns about potential adverse health effects caused by the diet. In general, people with type 1 diabetes are advised to follow an individualized eating plan.
The proportion of carbohydrate in a diet is not linked to the risk of type 2 diabetes, although there is some evidence that diets containing certain high-carbohydrate items – such as sugar-sweetened drinks or white rice – are associated with an increased risk. Some evidence indicates that consuming fewer carbohydrate foods may reduce biomarkers of type 2 diabetes.
A 2018 report on type 2 diabetes by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) found that a low-carbohydrate diet may not be as good as a Mediterranean diet for improving glycemic control, and that although having a healthy body weight is important, "there is no single ratio of carbohydrate, proteins, and fat intake that is optimal for every person with type 2 diabetes". There is no good evidence that low-carbohydrate diets are better than a conventional healthy diet, in which carbohydrates typically account for more than 40% of calories consumed. Low-carbohydrate dieting has no effect on the kidney function of people who have type 2 diabetes.
Limiting carbohydrate consumption generally results in improved glucose control, although without long-term weight loss. Low-carbohydrate diets can be useful to help people with type 2 diabetes lose weight, but that "no single approach has been proven to be consistently superior". According to the ADA, people with diabetes should be "developing healthy eating patterns rather than focusing on individual macronutrients, micronutrients, or single foods". They recommended that the carbohydrates in a diet should come from "vegetables, legumes, fruits, dairy (milk and yogurt), and whole grains", while highly-refined foods and sugary drinks should be avoided.
Exercise and fatigue
A low-carbohydrate diet has been found to reduce endurance capacity for intense exercise efforts, and depleted muscle glycogen following such efforts is only slowly replenished if a low-carbohydrate diet is taken. Inadequate carbohydrate intake during athletic training causes metabolic acidosis, which may be responsible for the impaired performance which has been observed.
The ketogenic diet is a high-fat, low-carbohydrate diet used to treat drug-resistant childhood epilepsy. In the 2010s, it became a fad diet for people wanting to lose weight. Users of the ketogenic diet may not achieve sustainable weight loss, as this requires strict carbohydrate abstinence, and maintaining the diet is difficult. Possible risks of using the ketogenic diet over the long term may include kidney stones, osteoporosis, or increased levels of uric acid, a risk factor for gout.
Ketogenic diet (low carbohydrate diet) practice for weight loss has reportedly increased mortality rate (especially from cancer and cardiovascular disease), but mortality increase was only associated with animal-based diets, whereas mortality was reduced with plant-based diets.
Low-carbohydrate diets can be associated with increased mortality, as can high-carbohydrate diets.
Template:Asof research has paid insufficient attention to the potential adverse effects of carbohydrate restricted dieting, particularly for micronutrient sufficiency, bone health and cancer risk. One meta-analysis reported that adverse effects could include "constipation, headache, halitosis, muscle cramp and general weakness".
Ketosis induced by a low-carbohydrate diet has led to reported cases of ketoacidosis, a life-threatening condition. This has led to the suggestion that ketoacidosis should be considered a potential hazard of low-carbohydrate dieting.
In a comprehensive systematic review of 2018, Churuangsuk and colleagues reported that other case reports give rise to concerns of other potential risks of low-carbohydrate dieting including hyperosmolar coma, Wernicke's encephalopathy, optic neuropathy from thiamine deficiency, acute coronary syndrome and anxiety disorder.
As of 2014 it appeared that with respect to the risk of death for people with cardiovascular disease, the kind of carbohydrates consumed are important; diets relatively higher in fiber and whole grains lead to reduced risk of death from cardiovascular disease compared to diets high in refined-grains.
In 1797, John Rollo reported on the results of treating two diabetic Army officers with a low-carbohydrate diet and medications. A very low-carbohydrate, ketogenic diet was the standard treatment for diabetes throughout the nineteenth century.
In 1863, William Banting, a formerly obese English undertaker and coffin maker, published "Letter on Corpulence Addressed to the Public", in which he described a diet for weight control giving up bread, butter, milk, sugar, beer, and potatoes. His booklet was widely read, so much so that some people used the term "Banting" for the activity now called "dieting".
In the early 1900s Frederick Madison Allen developed a highly restrictive short term regime which was described by Walter R. Steiner at the 1916 annual convention of the Connecticut State Medical Society as The Starvation Treatment of Diabetes Mellitus.:176–177 This diet was often administered in a hospital in order to better ensure compliance and safety.:179
Modern low-carbohydrate diets
Other low-carbohydrate diets in the 1960s included the Air Force diet and the Drinking Man's Diet. In 1972, Robert Atkins published Dr. Atkins Diet Revolution, which advocated the low-carbohydrate diet he had successfully used in treating people in the 1960s. The book was a publishing success, but was widely criticized by the mainstream medical community as being dangerous and misleading, thereby limiting its appeal at the time.
The concept of the glycemic index was developed in 1981 by David Jenkins to account for variances in speed of digestion of different types of carbohydrates. This concept classifies foods according to the rapidity of their effect on blood sugar levels – with fast-digesting simple carbohydrates causing a sharper increase and slower-digesting complex carbohydrates, such as whole grains, a slower one.
In 1992, Atkins published an update from his 1972 book, Dr. Atkins New Diet Revolution, and other doctors began to publish books based on the same principles. During the late 1990s and early 2000s, low-carbohydrate diets became some of the most popular diets in the US. By some accounts, up to 18% of the population was using one type of low-carbohydrate diet or another at the peak of their popularity. Food manufacturers and restaurant chains noted the trend, as it affected their businesses. Parts of the mainstream medical community have denounced low-carbohydrate diets as being dangerous to health, such as the AHA in 2001, and the American Kidney Fund in 2002.
- Seckold R, Fisher E, de Bock M, King BR, Smart CE (October 2018). "The ups and downs of low-carbohydrate diets in the management of Type 1 diabetes: a review of clinical outcomes". Diabet. Med. (Review). doi:10.1111/dme.13845. PMID 30362180.
Low‐carbohydrate diets are of interest for improving glycaemic outcomes in the management of Type 1 diabetes. There is limited evidence to support their routine use in the management of Type 1 diabetes.
- Last AR, Wilson SA (June 2006). "Low-carbohydrate diets". American Family Physician. 73 (11): 1942–8. PMID 16770923.
- Seidelmann SB, Claggett B, Cheng S, Henglin M, Shah A, Steffen LM, et al. (2018). "Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis". Lancet Public Health (Meta-analysis). 3 (9): e419–e428. doi:10.1016/S2468-2667(18)30135-X. PMID 30122560.
- Reynolds A, Mann J, Cummings J, Winter N, Mete E, Te Morenga L (10 January 2019). "Carbohydrate quality and human health: a series of systematic reviews and meta-analyses" (PDF). Lancet (Review). 393 (10170): 434–445. doi:10.1016/S0140-6736(18)31809-9. PMID 30638909.
- Churuangsuk C, Kherouf M, Combet E, Lean M (2018). "Low-carbohydrate diets for overweight and obesity: a systematic review of the systematic reviews". Obes Rev (Systematic review). 19 (12): 1700–1718. doi:10.1111/obr.12744. PMID 30194696.
- Schwartz MW, Seeley RJ, Zeltser LM, Drewnowski A, Ravussin E, Redman LM, et al. (2017). "Obesity Pathogenesis: An Endocrine Society Scientific Statement". Endocr Rev (Scientific statement). 38 (4): 267–296. doi:10.1210/er.2017-00111. PMC 5546881. PMID 28898979.
- Hall KD (2017). "A review of the carbohydrate-insulin model of obesity". Eur J Clin Nutr (Review). 71 (3): 323–326. doi:10.1038/ejcn.2016.260. PMID 28074888.
- Mansoor N, Vinknes KJ, Veierød MB, Retterstøl K (February 2016). "Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials". The British Journal of Nutrition. 115 (3): 466–79. doi:10.1017/S0007114515004699. PMID 26768850.
- Gjuladin-Hellon T, Davies IG, Penson P, Amiri Baghbadorani R (2018). "Effects of carbohydrate-restricted diets on low-density lipoprotein cholesterol levels in overweight and obese adults: a systematic review and meta-analysis". Nutr Rev (Systematic review). 77 (3): 161–180. doi:10.1093/nutrit/nuy049. PMID 30544168.
- Brouns F (2018). "Overweight and diabetes prevention: is a low-carbohydrate-high-fat diet recommendable?". Eur J Nutr (Review). 57 (4): 1301–1312. doi:10.1007/s00394-018-1636-y. PMC 5959976. PMID 29541907.
- Meng Y, Bai H, Wang S, Li Z, Wang Q, Chen L (2017). "Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: A systematic review and meta-analysis of randomized controlled trials". Diabetes Research and Clinical Practice. 131: 124–131. doi:10.1016/j.diabres.2017.07.006. PMID 28750216.
- American Diabetes Association Professional Practice Committee (2019). "Professional Practice Committee: Standards of Medical Care in Diabetes—2019". Diabetes Care. 42 (Supplement 1): s46–s60. doi:10.2337/dc19-S005. PMID 30559231.
- "Top 5 worst celeb diets to avoid in 2018". British Dietetic Association. 7 December 2017.
The British Dietetic Association (BDA) today revealed its much-anticipated annual list of celebrity diets to avoid in 2018. The line-up this year includes Raw Vegan, Alkaline, Pioppi and Ketogenic diets as well as Katie Price's Nutritional Supplements.
- Westman EC, Feinman RD, Mavropoulos JC, Vernon MC, Volek JS, Wortman JA, Yancy WS, Phinney SD (2007). "Low-carbohydrate nutrition and metabolism". Am. J. Clin. Nutr. (Review). 86 (2): 276–84. doi:10.1093/ajcn/86.2.276. PMID 17684196.
- Feinman RD, Pogozelski WK, Astrup A, Bernstein RK, Fine EJ, Westman EC, et al. (2015). "Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base". Nutrition (review). 31 (1): 1–13. doi:10.1016/j.nut.2014.06.011. PMID 25287761.
- Forouhi NG, Misra A, Mohan V, Taylor R, Yancy W (2018). "Dietary and nutritional approaches for prevention and management of type 2 diabetes". BMJ. 361: k2234. doi:10.1136/bmj.k2234. PMC 5998736. PMID 29898883.
- Hashimoto Y, Fukuda T, Oyabu C, Tanaka M, Asano M, Yamazaki M, Fukui M (2016). "Impact of low-carbohydrate diet on body composition: meta-analysis of randomized controlled studies". Obes Rev (Review). 17 (6): 499–509. doi:10.1111/obr.12405. PMID 27059106.
- "Diet review: Ketogenic diet for weight loss". TH Chan School of Public Health, Harvard University. 2019. Retrieved 30 June 2019.
- Giugliano D, Maiorino MI, Bellastella G, Esposito K (2018). "More sugar? No, thank you! The elusive nature of low carbohydrate diets". Endocrine (Review). 61 (3): 383–387. doi:10.1007/s12020-018-1580-x. PMID 29556949.
- "Dietary Reference Intakes (DRIs)" (PDF). National Academy of Medicine. Archived from the original (PDF) on 19 October 2015. Retrieved 31 August 2015.
- Food and Nutrition Board (2002/2005). Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: The National Academies Press. Page 769 Archived 12 September 2006 at the Wayback Machine. ISBN 0-309-08537-3
- Belluz J (20 February 2018). "We've long blamed carbs for making us fat. What if that's wrong?". Vox.
- Barclay E (20 September 2012). "Billionaires Fund A 'Manhattan Project' For Nutrition And Obesity". WBUR News.
- Waite E (8 August 2018). "The Struggles of a $40 Million Nutrition Science Crusade". Wired.
- Hu T, Mills KT, Yao L, Demanelis K, Eloustaz M, Yancy WS, Kelly TN, He J, Bazzano LA (October 2012). "Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials". American Journal of Epidemiology. 176 Suppl 7 (Suppl 7): S44–54. doi:10.1093/aje/kws264. PMC 3530364. PMID 23035144.
- Schwingshackl L, Chaimani A, Schwedhelm C, Toledo E, Pünsch M, Hoffmann G, et al. (2018). "Comparative effects of different dietary approaches on blood pressure in hypertensive and pre-hypertensive patients: A systematic review and network meta-analysis". Crit Rev Food Sci Nutr (Systematic Review): 1–14. doi:10.1080/10408398.2018.1463967. PMID 29718689.
- Public Health England (2015). "Carbohydrates and Health" (Report). Scientific Advisory Council on Nutrition: 57, 85 – via The Stationery Office.
No significant association was found between total carbohydrate intake as g/day and incidence of type 2 diabetes mellitus.Cite journal requires
- van Zuuren EJ, Fedorowicz Z, Kuijpers T, Pijl H (August 2018). "Effects of low-carbohydrate- compared with low-fat-diet interventions on metabolic control in people with type 2 diabetes: a systematic review including GRADE assessments". The American Journal of Clinical Nutrition. 108 (2): 300–331. doi:10.1093/ajcn/nqy096. PMID 30007275.
- Davies MJ, D'Alessio DA, Fradkin J, Kernan WN, Mathieu C, Mingrone G, et al. (2018). "Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)". Diabetes Care. 41 (12): 2669–2701. doi:10.2337/dci18-0033. PMC 6245208. PMID 30291106.
Low-carbohydrate, low glycemic index, and high-protein diets, and the Dietary Approaches to Stop Hypertension (DASH) diet all improve glycemic control, but the effect of the Mediterranean eating pattern appears to be the greatest
- Suyoto PST (2018). "Effect of low-carbohydrate diet on markers of renal function in patients with type 2 diabetes: A meta-analysis". Diabetes Metab Res Rev (Meta-analysis). 34 (7): e3032. doi:10.1002/dmrr.3032. PMID 29904998.
- Meng Y, Bai H, Wang S, Li Z, Wang Q, Chen L (September 2017). "Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: A systematic review and meta-analysis of randomized controlled trials". Diabetes Research and Clinical Practice. 131: 124–131. doi:10.1016/j.diabres.2017.07.006. PMID 28750216.
- Maughan RJ, Greenhaff PL, Leiper JB, Ball D, Lambert CP, Gleeson M (1997). "Diet composition and the performance of high-intensity exercise". J Sports Sci (Review). 15 (3): 265–75. doi:10.1080/026404197367272. PMID 9232552.
- Martin-McGill KJ, Jackson CF, Bresnahan R, Levy RG, Cooper PN (7 November 2018). "Ketogenic diets for drug-resistant epilepsy". Cochrane Database Syst Rev. 11: CD001903. doi:10.1002/14651858.CD001903.pub4. PMID 30403286.CS1 maint: uses authors parameter (link)
- Kosinski C, Jornayvaz FR (2017). "Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies". Nutrients (journal). 9 (5): e517. doi:10.3390/nu9050517. PMC 5452247. PMID 28534852.
- Seidelmann SB, Claggett B, Cheng S, Henglin M, Shah A, Steffen LM, Folsom AR, Rimm EB, Willett WC, Solomon SD (2018). "Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis". The Lancet:Public Health. 3 (9): e419–e428. doi:10.1016/S2468-2667(18)30135-X. PMC 6339822. PMID 30122560.
- Ullah W, Hamid M, Mohammad Ammar Abdullah H, Ur Rashid M, Inayat F (January 2018). "Another "D" in MUDPILES? A Review of Diet-Associated Nondiabetic Ketoacidosis". Journal of Investigative Medicine High Impact Case Reports. 6: 232470961879626. doi:10.1177/2324709618796261. PMC 6108016. PMID 30151400.
- "Healthy Weight—The truth about carbs". National Health Service. 19 December 2018.
- Hu T, Bazzano LA (April 2014). "The low-carbohydrate diet and cardiovascular risk factors: evidence from epidemiologic studies". Nutrition, Metabolism, and Cardiovascular Diseases. 24 (4): 337–43. doi:10.1016/j.numecd.2013.12.008. PMC 4351995. PMID 24613757.
- Groves B (2002). "William Banting Father of the Low-Carbohydrate Diet". The Weston A. Price Foundation.
- Steiner WR (1916). "The Starvation Treatment of Diabetes Mellitus". Proceedings of the Connecticut State Medical Society: 176–184.
124th Annual Convention
- Another publication of similar regimen was
- Gordon E, Goldberg M, Chosy G (October 1963). "A New Concept in the Treatment of Obesity". JAMA. 186 (1): 50–60. doi:10.1001/jama.1963.63710010013014. PMID 14046659.
- "A critique of low-carbohydrate ketogenic weight reduction regimens. A review of Dr. Atkins' diet revolution". JAMA. 224 (10): 1415–9. June 1973. doi:10.1001/jama.1973.03220240055018. PMID 4739993.
- Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV (March 1981). "Glycemic index of foods: a physiological basis for carbohydrate exchange". The American Journal of Clinical Nutrition. 34 (3): 362–6. doi:10.1093/ajcn/34.3.362. PMID 6259925.
- "PBS News Hour: Low Carb Craze". Pbs.org. Retrieved 18 December 2011.
- Reinberg, Steven. "Americans Look for Health on the Menu: Survey finds nutrition plays increasing role in dining-out choices". Archived from the original on 28 September 2007. Retrieved 28 September 2007.
- Schooler L (22 June 2004). "Low-Carb Diets Trim Krispy Kreme's Profit Line". Morning Edition. National Public Radio. Retrieved 18 December 2011.
- St Jeor ST, Howard BV, Prewitt TE, Bovee V, Bazzarre T, Eckel RH (October 2001). "Dietary protein and weight reduction: a statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association". Circulation. 104 (15): 1869–74. doi:10.1161/hc4001.096152. PMID 11591629.
These diets are generally associated with higher intakes of total fat, saturated fat, and cholesterol because the protein is provided mainly by animal sources. ... Beneficial effects on blood lipids and insulin resistance are due to the weight loss, not to the change in caloric composition. ... High-protein diets may also be associated with increased risk for coronary heart disease due to intakes of saturated fat, cholesterol, and other associated dietary factors.
- The American Kidney Fund: American Kidney Fund Warns About Impact of High-Protein Diets on Kidney Health: 25 April 2002