Lubiprostone
Lubiprostone (pronounced loo-bi-PROS-tone) is a medication used in the management of chronic idiopathic constipation, irritable bowel syndrome (IBS) with constipation, and opioid-induced constipation. It is marketed under the trade name Amitiza.
Etymology
The name "Lubiprostone" is derived from its chemical structure. The "lubi-" prefix is a reference to its lubricating properties, and the "-prostone" suffix indicates that it is a type of prostaglandin derivative.
Pharmacology
Lubiprostone works by increasing the secretion of chloride ions in the intestines. This increases the amount of water in the intestines, which can help soften stools and stimulate bowel movements. It is classified as a chloride channel activator.
Usage
Lubiprostone is typically taken orally, with food and water. The dosage may vary depending on the specific condition being treated. It is important to follow the prescribing doctor's instructions when taking this medication.
Side Effects
Common side effects of Lubiprostone include nausea, diarrhea, and abdominal pain. More serious side effects can include chest tightness or shortness of breath. If these occur, medical attention should be sought immediately.
Related Terms
- Chronic idiopathic constipation
- Irritable bowel syndrome
- Opioid-induced constipation
- Prostaglandin
- Chloride channel activator
External links
- Medical encyclopedia article on Lubiprostone
- Wikipedia's article - Lubiprostone
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