Macimorelin

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Macimorelin

Macimorelin (pronounced as ma-si-mo-re-lin) is a pharmaceutical drug used in the diagnosis of adult growth hormone deficiency (AGHD). It is marketed under the brand name Macrilen.

Etymology

The name "Macimorelin" is derived from its chemical structure. The prefix "maci-" is derived from the Latin word "macire", which means to nourish or to grow. The suffix "-morelin" is a common suffix used in the names of peptides, indicating its role in stimulating a biological response.

Usage

Macimorelin is an orally active ghrelin agonist that stimulates the release of growth hormone from the pituitary gland. It is used in a test to assess growth hormone deficiency in adults, a condition that can cause various health problems including poor bone health, cardiovascular disease, and decreased quality of life.

Related Terms

  • Ghrelin: A hormone that stimulates hunger. Macimorelin works by mimicking the effects of ghrelin.
  • Pituitary gland: A small gland at the base of the brain that produces several important hormones, including growth hormone.
  • Growth hormone: A hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals.
  • Adult Growth Hormone Deficiency (AGHD): A medical condition characterized by inadequate secretion of growth hormone from the pituitary gland.

Side Effects

Common side effects of Macimorelin include diarrhea, headache, and changes in taste. More serious side effects may include an irregular heartbeat or a prolonged QT interval, which can lead to serious heart problems.

See Also

External links

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