Macimorelin acetate

From WikiMD.org
Jump to navigation Jump to search

Macimorelin acetate (pronunciation: ma-si-mo-re-lin a-ce-tate) is a growth hormone secretagogue receptor agonist. It is used as a diagnostic agent in the evaluation of adult growth hormone deficiency (AGHD).

Etymology

The term "Macimorelin" is derived from its chemical structure, which is a synthetic peptide analogue of ghrelin, a hormone that stimulates the release of growth hormone. "Acetate" refers to the salt form of the drug, which enhances its stability and absorption in the body.

Pharmacology

Macimorelin acetate works by stimulating the pituitary gland to release growth hormone. It binds to the growth hormone secretagogue receptor in the pituitary gland, which leads to the release of growth hormone into the bloodstream. This mechanism of action is similar to that of natural ghrelin, but macimorelin is more potent and has a longer duration of action.

Clinical Use

Macimorelin acetate is used as a diagnostic agent in the evaluation of adult growth hormone deficiency (AGHD). It is administered orally in a single dose, and the patient's blood is then tested at regular intervals to measure the levels of growth hormone. If the levels are below a certain threshold, this indicates a deficiency of growth hormone.

Side Effects

Common side effects of macimorelin acetate include diarrhea, headache, and changes in taste. Less common side effects can include dizziness, fatigue, and upper respiratory tract infection.

Related Terms

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski