Macrocyte
Macrocyte
Macrocyte (/mækˈroʊsaɪt/; from the Greek words makros meaning "large" and kytos meaning "cell") is a term used in hematology to describe a red blood cell that is larger than normal.
Definition
A macrocyte is a type of red blood cell that has a larger size than the average red blood cell. The normal diameter of a red blood cell is typically between 6 and 8 micrometers. However, a macrocyte has a diameter of more than 8 micrometers.
Causes
Macrocytes can be caused by a variety of conditions, including vitamin B12 deficiency, folate deficiency, and alcoholism. They can also be a result of certain medications, such as those used to treat HIV or cancer.
Diagnosis
Macrocytosis, the presence of macrocytes, is usually detected through a complete blood count (CBC) test. This test measures the size and number of red blood cells in a sample of blood. If the mean corpuscular volume (MCV) is high, it indicates that the red blood cells are larger than normal, suggesting the presence of macrocytes.
Treatment
Treatment for macrocytosis typically involves addressing the underlying cause. For example, if the macrocytes are caused by a vitamin B12 or folate deficiency, the treatment may involve dietary changes or supplements. If the macrocytes are caused by medication, the prescribing doctor may need to adjust the dosage or switch to a different medication.
Related Terms
- Anemia: A condition characterized by a lack of healthy red blood cells or hemoglobin.
- Microcyte: A red blood cell that is smaller than normal.
- Normocyte: A red blood cell of normal size and appearance.
External links
- Medical encyclopedia article on Macrocyte
- Wikipedia's article - Macrocyte
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