Maraviroc

From WikiMD.org
Jump to navigation Jump to search

Maraviroc (pronounced: ma-ra-vi-roc) is an antiretroviral drug used in the treatment of HIV infection. It is a member of the CCR5 receptor antagonist class of antiretrovirals and is marketed under the brand name Selzentry (in the US) and Celsentri (outside of the US).

Etymology

The name "Maraviroc" is derived from the class of drugs it belongs to, CCR5 receptor antagonists. The "maravi" part of the name is a reference to the Maravi people, who are known for their resistance to certain diseases, including HIV.

Pharmacology

Maraviroc works by blocking the CCR5 co-receptor located on the surface of certain immune cells. This prevents the HIV virus from entering these cells and thus slows down or stops the spread of the virus in the body.

Usage

Maraviroc is used in combination with other antiretroviral drugs for the treatment of HIV-1 infection in adults who have CCR5-tropic HIV-1 infection. It is not recommended for use in individuals with dual/mixed or CXCR4-tropic HIV-1, as these types of the virus do not use the CCR5 co-receptor to enter cells.

Side Effects

Common side effects of Maraviroc include cough, fever, upper respiratory tract infections, rash, musculoskeletal symptoms, abdominal pain, and dizziness. Severe side effects may include liver damage, heart problems, and severe skin reactions.

See Also

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski