Mariptiline
Mariptiline
Mariptiline (pronunciation: /məˈrɪptɪliːn/) is a tricyclic antidepressant (TCA) that was developed in the 1970s by the Japanese pharmaceutical company Takeda. It is primarily used in the treatment of depression.
Etymology
The name "Mariptiline" is derived from the chemical structure of the drug, which is a tricyclic compound. The prefix "Mari-" is derived from the Latin word "marinus", meaning "of the sea", referring to the three-ring structure of the compound that resembles a trident, a three-pronged spear traditionally associated with the sea god Neptune. The suffix "-ptiline" is a common ending for tricyclic antidepressants, derived from the word "triptoline", the first TCA to be discovered.
Usage
Mariptiline is used primarily to treat major depressive disorder (MDD). It works by inhibiting the reuptake of certain neurotransmitters in the brain, specifically norepinephrine and serotonin, thereby increasing their levels in the brain and improving mood.
Related Terms
- Tricyclic antidepressant (TCA): A class of drugs that Mariptiline belongs to. They are named for their three-ring chemical structure.
- Depression: A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
- Norepinephrine: A neurotransmitter involved in the regulation of mood and anxiety.
- Serotonin: A neurotransmitter that contributes to feelings of well-being and happiness.
Side Effects
Like other TCAs, Mariptiline can cause a number of side effects, including dry mouth, blurred vision, constipation, urinary retention, and drowsiness. It can also cause more serious side effects such as cardiac arrhythmias, particularly in overdose.
See Also
External links
- Medical encyclopedia article on Mariptiline
- Wikipedia's article - Mariptiline
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