Mast

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Mast

Mast (/mæst/), in the medical context, refers to a type of cell found in the body known as a Mast cell. These cells play a crucial role in the body's immune response, particularly in the occurrence of allergic reactions and other hypersensitivity reactions.

Etymology

The term "Mast" is derived from the German word "Mastzelle", which translates to "fattening cell". This term was coined by Paul Ehrlich, a German physician and scientist, in the late 19th century due to the cell's large granules being mistaken for nourishment or "fattening" of the cell.

Related Terms

  • Mast cell: A type of white blood cell that is part of the immune system and plays a key role in the body's defense mechanisms, particularly in allergic reactions and other hypersensitivity responses.
  • Mastocytosis: A condition characterized by an excessive number of mast cells in the body, which can lead to a variety of symptoms, including skin lesions, abdominal discomfort, and anaphylaxis.
  • Mast Cell Activation Syndrome (MCAS): A disorder where mast cells inappropriately and excessively release chemical mediators, resulting in a range of chronic symptoms, sometimes including anaphylaxis or near-anaphylaxis attacks.
  • Anaphylaxis: A severe, potentially life-threatening allergic reaction that can occur rapidly, often in response to foods, medications, or insect stings. Mast cells play a significant role in the occurrence of anaphylaxis.

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