Mean platelet volume
Mean Platelet Volume (MPV)
Mean Platelet Volume (MPV) is a measure of the average size of platelets in the blood. Pronounced as /mi:n 'pleɪtlɪt 'vɒlju:m/, the term originates from the English words "mean" (average), "platelet" (type of blood cell), and "volume" (size).
Definition
MPV is a laboratory value that represents the average size of platelets in a blood sample. It is part of a standard Complete Blood Count (CBC) test and is often used in diagnosing and monitoring certain medical conditions.
Clinical Significance
An increased MPV can be a sign of various medical conditions, including thrombocytopenia, myeloproliferative disorders, and cardiovascular disease. Conversely, a decreased MPV can indicate conditions such as aplastic anemia and thrombocytosis.
Measurement
MPV is measured in femtoliters (fL) and is typically between 7.5 and 11.5 fL in healthy individuals. The measurement is done using an automated machine that counts and sizes the platelets in a blood sample.
Related Terms
- Platelet Distribution Width (PDW): Another measure of platelet size variability in a blood sample.
- Plateletcrit (PCT): The volume percentage of platelets in the blood.
- Thrombocytopenia: A condition characterized by abnormally low levels of platelets in the blood.
- Thrombocytosis: A condition characterized by abnormally high levels of platelets in the blood.
External links
- Medical encyclopedia article on Mean platelet volume
- Wikipedia's article - Mean platelet volume
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