Metabolome
Metabolome
The Metabolome (/mɪˈtæbəloʊm/), derived from the Greek words metabole meaning change and -ome signifying a mass or collection, is the complete set of small-molecule chemicals found within a biological sample, such as a single organism or a group of organisms. The metabolome represents the final downstream products of gene expression and thus provides a snapshot of the physiological state of an organism.
Etymology
The term "Metabolome" is a combination of "Metabolism" and "-ome". "Metabolism" comes from the Greek metabole which means change, and -ome is a suffix used in molecular biology to denote a complete set of something, in this case, metabolites.
Related Terms
- Metabolomics: The scientific study of the metabolome, often used to discover biomarkers for disease or to understand the effects of genetic modification.
- Metabolite: A small molecule that is the product of metabolism.
- Metabolic pathway: A series of chemical reactions in a cell that build up or break down molecules for cellular processes.
- Genome: The complete set of genes or genetic material present in a cell or organism.
- Proteome: The entire set of proteins expressed by a genome, cell, tissue, or organism at a certain time.
- Transcriptome: The sum of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced in one or a population of cells.
See Also
References
External links
- Medical encyclopedia article on Metabolome
- Wikipedia's article - Metabolome
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