Metamizole
Metamizole
Metamizole (pronounced: met-uh-MIZ-ole), also known as Dipyrone, is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used as an analgesic and antipyretic.
Etymology
The term "Metamizole" is derived from its chemical name, 1-phenyl-2,3-dimethyl-5-pyrazolone sodium methanesulfonate.
Usage
Metamizole is used to treat severe acute pain, particularly when other analgesics are not suitable. It is also used to lower fever and to relieve spasms. However, due to its potential for causing agranulocytosis, its use is limited in many countries.
Mechanism of Action
Metamizole works by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain. It also has a direct effect on the thermoregulatory center in the hypothalamus, which helps to reduce fever.
Side Effects
Common side effects of Metamizole include nausea, vomiting, abdominal pain, and diarrhea. Serious side effects can include agranulocytosis, a condition that affects the body's ability to fight off infection.
Related Terms
- Nonsteroidal anti-inflammatory drug (NSAID): A type of medication used to reduce inflammation and pain.
- Analgesic: A medication used to relieve pain.
- Antipyretic: A medication used to reduce fever.
- Agranulocytosis: A condition characterized by a decrease in the number of white blood cells, which can increase the risk of infection.
External links
- Medical encyclopedia article on Metamizole
- Wikipedia's article - Metamizole
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