Methoxamine
Methoxamine
Methoxamine (pronunciation: me-thox-a-mine) is a vasoconstrictor used in the treatment of hypotension. It is a synthetic sympathomimetic agent that primarily stimulates alpha-adrenergic receptors.
Etymology
The term "Methoxamine" is derived from its chemical structure, which includes a methoxy group (-OCH3) and an amine group (-NH2).
Usage
Methoxamine is used to increase both systemic and pulmonary arterial blood pressure. It is also used as a tool in neuroscience research to induce a pressor response, which is a rise in blood pressure.
Pharmacology
Methoxamine works by stimulating alpha-adrenergic receptors, which results in vasoconstriction and an increase in blood pressure. It is a direct-acting sympathomimetic with potent vasoconstrictor activity.
Related Terms
- Vasoconstrictor: A drug that constricts (narrows) blood vessels, thereby restricting blood flow.
- Hypotension: Abnormally low blood pressure.
- Sympathomimetic: A drug that mimics the postganglionic sympathetic neurotransmitters such as norepinephrine and epinephrine.
- Alpha-adrenergic receptors: Receptors in the nervous system that respond to the neurotransmitter norepinephrine and the hormone epinephrine.
See Also
- Vasopressor: A group of medicines that contract (tighten) blood vessels and increase blood pressure.
- Phenylephrine: A medication primarily used to increase blood pressure in acute hypotensive states.
External links
- Medical encyclopedia article on Methoxamine
- Wikipedia's article - Methoxamine
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