From WikiMD
Jump to navigation Jump to search

Information about Moxifloxacin

Moxifloxacin is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria as well as atypical pathogens.

Liver safety of Moxifloxacin

Moxifloxacin has been linked to mild ALT elevations during therapy and to rare instances of idiosyncratic acute liver injury with symptoms and jaundice.

Mechanism of action of Moxifloxacin

Moxifloxacin (mox" i flox' a sin) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria including multidrug resistant strains of Streptococcus pneumoniae. Like other fluoroquinolones, moxifloxacin is active against a wide range of aerobic gram-positive and gram-negative organisms. The quinolones are believed to act by inhibition of type II DNA toposiomerases (gyrases) that are required for synthesis of bacterial mRNAs (transcription) and DNA replication.

FDA approval information for Moxifloxacin

Moxifloxacin was approved for use in the United States in 1999 and is available generically and under the commercial names of Avelox, Moxeza and Vigamox. Current indications include mild-to-moderate bacterial infections such as sinusitis, bronchitis, community acquired pneumonia, skin infections, cellulitis, abcesses and complicated intraabdominal infections due to sensitive organisms. Moxifloxacin is available in formulations of 400 mg tablets, the usual dose being 400 mg daily for 5 to 14 days. Intravenous formulations are available for moderate to severe infections, the usual IV dosages being 400 mg daily.

Side effects of Moxifloxacin

Common side effects include gastrointestinal upset, headaches, skin rash and allergic reactions. Less common but more severe side effects of the fluoroquinolones include prolongation of the QT interval, seizures, hallucinations, tendon rupture, angioedema and photosensitivity.

List of flouroquinolones

Cost and Coupons - Moxifloxacin

Reviews for Moxifloxacin

Wellness that matters!

Articles on Moxifloxacin

This article is a stub. YOU can help Wikimd by expanding it!

Learn more about Moxifloxacin

Drug classes

WikiMD Resources for Moxifloxacin


Most recent articles

Most cited

Review articles

Articles on Moxifloxacin in N Eng J Med, Lancet, BMJ

Media Moxifloxacin

Powerpoint slides

Podcasts and MP3's


Evidence Based Medicine

Cochrane Collaboration

Clinical Trials

Ongoing Trials on Moxifloxacin

Trial results on Moxifloxacin

Clinical Trials on Moxifloxacin at Google

Books and news

Books on Moxifloxacin

Moxifloxacin in the news

Commentary Moxifloxacin

Blogs on Moxifloxacin

Patient Resources / Community

Patient resources

Discussion groups

Patient Handouts

Other resources

Social Media

YouTube videos

W8MD Weight Loss, Sleep & MedSpa

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U |V | W | X | Y | Z

Ad. Tired of being overweight? W8MD's insurance weight loss program can HELP* | Lose weight King of Prussia, PA | Lose weight NYC | Lose weight NJ | Lose weight Philadelphia Advertise

Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer. * Individual results may vary for weight loss from our sponsors.

Our sponsors WikiMD is supported by W8MD weight loss, sleep and medical aesthetic centers.