Mycosis Fungoides
Mycosis Fungoides
Mycosis Fungoides (pronounced: my-KO-sis fun-GOY-deez) is a rare form of cutaneous T-cell lymphoma that primarily affects the skin. The term originates from the Greek words "mykes" meaning fungus and "oides" meaning like, due to the mushroom-like skin tumors seen in advanced stages of the disease.
Definition
Mycosis Fungoides is a type of non-Hodgkin lymphoma where white blood cells called T-cells become malignant and affect the skin. It is characterized by red, scaly patches or plaques on the skin that may progress to form mushroom-like skin tumors.
Symptoms
The symptoms of Mycosis Fungoides may vary depending on the stage of the disease. Early stages may present with skin symptoms such as rash, itching, and patches or plaques. In advanced stages, tumors may form on the skin and the disease may spread to other parts of the body including the lymph nodes, blood, and internal organs.
Causes
The exact cause of Mycosis Fungoides is unknown. However, it is believed to be related to changes in the DNA of T-cells, a type of white blood cell that fights infections.
Diagnosis
Diagnosis of Mycosis Fungoides involves a thorough physical examination, medical history, and skin biopsy. Additional tests such as blood tests, imaging studies, and lymph node biopsy may be required to determine the extent of the disease.
Treatment
Treatment options for Mycosis Fungoides depend on the stage of the disease and may include skin-directed therapies, systemic therapies, and radiation therapy. In some cases, stem cell transplant may be considered.
Prognosis
The prognosis of Mycosis Fungoides varies widely and depends on the stage of the disease at diagnosis, the patient's overall health, and the response to treatment.
Related Terms
External links
- Medical encyclopedia article on Mycosis Fungoides
- Wikipedia's article - Mycosis Fungoides
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