NRTI

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NRTI

NRTI (pronounced as /ɛn ɑːr ti aɪ/), also known as Nucleoside Reverse Transcriptase Inhibitors, is a type of antiretroviral drug used in the treatment of HIV and Hepatitis B.

Etymology

The term "NRTI" is an acronym derived from the full name of the drug class, Nucleoside Reverse Transcriptase Inhibitors. The term "nucleoside" refers to the structural component of the drug, which is similar to the building blocks of DNA. "Reverse transcriptase inhibitors" refers to the action of the drug, which inhibits the enzyme reverse transcriptase, a critical component in the replication of HIV and Hepatitis B viruses.

Usage

NRTIs are used in combination with other antiretroviral drugs to form a complete antiretroviral therapy (ART) regimen. They work by inhibiting the reverse transcriptase enzyme, thereby preventing the virus from replicating within the body. Some commonly used NRTIs include Abacavir, Lamivudine, and Zidovudine.

Related Terms

  • Antiretroviral Therapy: The use of a combination of drugs to treat HIV and prevent the progression to AIDS.
  • Reverse Transcriptase: An enzyme that converts RNA into DNA, which is a critical step in the replication of retroviruses like HIV.
  • DNA: Deoxyribonucleic acid, the molecule that carries genetic information in all living organisms.
  • RNA: Ribonucleic acid, a molecule similar to DNA that plays several key roles in the coding, decoding, regulation, and expression of genes.

See Also

External links

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