NTRK gene fusion

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NTRK gene fusion
TermNTRK gene fusion
Short definitionNSC 655649 - A substance being studied for the treatment of cancer. It belongs to the drug families called antitumor antibiotics and topoisomerase inhibitors. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


NTRK gene fusion - mutation (change) that occurs when a piece of the chromosome that contains a gene called NTRK breaks off and joins a gene on another chromosome. NTRK gene fusions result in abnormal proteins called TRK fusion proteins that can cause cancer cells to grow. NTRK gene fusions can be found in some cancers, including cancers of the brain, head and neck, thyroid, soft tissue, lung and colon. Also called neurotrophic tyrosine receptor kinase gene fusion

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