Nadp
NADP (pronounced as N-A-D-P, /ˈen.eɪ.diː.piː/) is an acronym for Nicotinamide Adenine Dinucleotide Phosphate, a coenzyme used in anabolic reactions, which require NADPH as a reducing agent.
Etymology
The term NADP is derived from its full form, Nicotinamide Adenine Dinucleotide Phosphate. The term 'Nicotinamide' is derived from niacin, also known as nicotinic acid or vitamin B3. 'Adenine' is one of the two purine nucleobases used in forming nucleotides of the nucleic acids DNA and RNA. 'Dinucleotide' refers to a type of molecule that consists of two nucleotides joined by their phosphate groups. 'Phosphate' is a chemical compound that contains the phosphate ion.
Function
NADP is a coenzyme that functions as a universal electron carrier, accepting electrons and hydrogen atoms to form NADPH, or nicotinamide adenine dinucleotide phosphate. NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species, allowing the regeneration of glutathione (GSH).
Related Terms
- NADPH: The reduced form of NADP.
- Coenzyme: A non-protein compound necessary for the functioning of an enzyme.
- Nucleotide: Organic molecules that serve as the monomers, or subunits, of nucleic acids like DNA and RNA.
- Glutathione: An antioxidant in plants, animals, fungi, and some bacteria and archaea, preventing damage to important cellular components.
See Also
External links
- Medical encyclopedia article on Nadp
- Wikipedia's article - Nadp
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