Nigro protocol
Nigro Protocol
The Nigro Protocol (pronunciation: /ˈniːɡroʊ/), also known as the Nigro regimen, is a preoperative treatment protocol primarily used in the management of anal cancer. It was first introduced by Dr. Norman Nigro in the 1970s.
Etymology
The term "Nigro Protocol" is derived from the name of its originator, Dr. Norman Nigro, a renowned American oncologist who pioneered the use of combined chemotherapy and radiation therapy for anal cancer.
Description
The Nigro Protocol involves the administration of chemotherapy drugs, typically 5-fluorouracil (5-FU) and mitomycin C, in conjunction with radiation therapy. This combined modality approach aims to preserve the anal sphincter and avoid the need for a colostomy, thereby improving the patient's quality of life.
Related Terms
- Chemoradiation: The combination of chemotherapy and radiation therapy used in the Nigro Protocol.
- Anal cancer: The type of cancer for which the Nigro Protocol is primarily used.
- 5-fluorouracil: A chemotherapy drug used in the Nigro Protocol.
- Mitomycin C: Another chemotherapy drug used in the Nigro Protocol.
- Radiation therapy: A treatment method used in the Nigro Protocol.
- Colostomy: A surgical procedure that the Nigro Protocol aims to avoid.
See Also
External links
- Medical encyclopedia article on Nigro protocol
- Wikipedia's article - Nigro protocol
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