Nissl body
Nissl Body
Nissl bodies (pronounced: /ˈnɪsəl/), also known as Nissl substance or tigroid bodies, are large granular bodies found in neurons. They are named after the German psychiatrist and neuropathologist Franz Nissl, who first described them at the end of the 19th century.
Etymology
The term "Nissl body" is derived from the name of its discoverer, Franz Nissl. The term "tigroid bodies" comes from the Greek word "tigris," meaning tiger, due to the striped appearance of these bodies under a microscope.
Definition
Nissl bodies are basophilic granules found in the cell body and dendrites, but not the axon, of neurons. They are made up of rough endoplasmic reticulum and free ribosomes, and are the site of protein synthesis.
Function
The primary function of Nissl bodies is to produce proteins for the nerve cell. They are particularly active in neurons that are regenerating or synthesizing large amounts of protein.
Related Terms
- Neuron: The basic working unit of the brain, a specialized cell designed to transmit information to other nerve cells, muscle, or gland cells.
- Endoplasmic reticulum: A type of organelle in the cells of eukaryotic organisms that forms an interconnected network of flattened, membrane-enclosed sacs or tubes known as cisternae.
- Ribosome: A complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis.
- Protein synthesis: The process in which cells build proteins.
See Also
External links
- Medical encyclopedia article on Nissl body
- Wikipedia's article - Nissl body
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