Nivolumab

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Nivolumab
TermNivolumab
Short definitionNitrosourea - (pronounced) (ny-TROH-soh-YOO-ree-uh) A cancer drug that can cross the blood-brain barrier. Carmustine and lomustine are nitrosoureas 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


Nivolumab - (pronounced) (nih-VOL-yoo-mab) drug that binds to the protein PD-1 to help immune cells kill cancer cells better and is used to treat many different types of cancer. These include cancers that express the protein PD-L1 or have certain mutations (changes) in genes involved in DNA repair. Nivolumab is used alone or with other medicines to treat certain types of cancer of the esophagus, gastroesophageal junction, stomach cancer, colorectal cancer, non-small cell lung cancer, renal cell carcinoma (a type of kidney cancer), melanoma, hepatocellular carcinoma (a type of liver cancer), squamous cell carcinoma head and neck, classic Hodgkin's lymphoma, urothelial carcinoma (a type of bladder or urinary tract cancer) and malignant pleural mesothelioma. It is also being studied in the treatment of other types of cancer. Nivolumab can block PD-1 and help the immune system kill cancer cells. It's a type of monoclonal antibody and a type of immune checkpoint inhibitor. Also called Opdivo

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