Opioid receptors
Opioid Receptors
Opioid receptors (/oʊˈpiːɔɪd rɪˈsɛptərz/) are a group of G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatostatin receptors (SSTRs).
Etymology
The term "opioid" originates from the Greek words "opion" meaning "poppy juice" and "eidos" meaning "like". The term "receptor" is derived from the Latin "recipere" meaning "to receive". Thus, "opioid receptor" refers to a receptor that receives opioids.
Types of Opioid Receptors
There are four major types of opioid receptors in the body: mu-opioid receptor (MOR), delta-opioid receptor (DOR), kappa-opioid receptor (KOR), and nociceptin receptor (NOP). Each receptor type has a different function and is activated by different types of opioids.
Mu-Opioid Receptor
The mu-opioid receptor (MOR) is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone.
Delta-Opioid Receptor
The delta-opioid receptor (DOR) is thought to play a role in analgesia, depression, anxiety, and epilepsy.
Kappa-Opioid Receptor
The kappa-opioid receptor (KOR) is involved in pain control, stress response, and addictive behavior.
Nociceptin Receptor
The nociceptin receptor (NOP), also known as the ORL1 receptor, is involved in pain control, anxiety, and depression.
Related Terms
- G protein-coupled receptors
- Somatostatin receptors
- Mu-opioid receptor
- Delta-opioid receptor
- Kappa-opioid receptor
- Nociceptin receptor
External links
- Medical encyclopedia article on Opioid receptors
- Wikipedia's article - Opioid receptors
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski