Oral allergy syndrome

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Oral Allergy Syndrome

Oral allergy syndrome (OAS), also known as pollen-food allergy syndrome (PFAS), is a type of food allergy characterized by a cluster of allergic reactions in the mouth in response to eating certain (usually fresh) fruits, nuts, and vegetables that typically develops in adults with hay fever.

Pronunciation

Oral Allergy Syndrome: /ˈɔːrəl ˈælərdʒi sɪnˈdroʊm/

Etymology

The term "Oral Allergy Syndrome" is derived from the Latin word "os, oris" meaning mouth, the Greek word "allergia" meaning hypersensitivity, and the Greek word "syndromos" meaning concurrence.

Symptoms

OAS symptoms include itchy or tingly mouth, throat, or lips, swelling of the lips, tongue, throat, and inside of the mouth, difficulty swallowing, and in severe cases, anaphylaxis. These symptoms usually occur rapidly after eating or tasting a triggering food, and can be worse during the pollen season.

Causes

OAS is caused by cross-reacting allergens found in both pollen and raw fruits, vegetables, or nuts. The immune system recognizes the pollen and similar proteins in the food and directs an allergic response to it. The most common type of OAS in Northern Europe is birch-pollen related OAS, but it can also be caused by other types of pollen such as grass, ragweed or mugwort.

Diagnosis

Diagnosis of OAS is usually based on patient history and clinical examination. Skin prick tests or blood tests can be used to confirm the diagnosis.

Treatment

Treatment for OAS is mainly avoiding the triggering foods. Cooking or peeling the food may allow it to be eaten without a reaction. In some cases, immunotherapy may be recommended.

Related Terms

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