Orthokeratosis
Orthokeratosis
Orthokeratosis (pronounced: or-tho-ker-a-toe-sis) is a term used in dermatology and histopathology to describe a specific change in the stratum corneum, the outermost layer of the epidermis. It refers to the presence of a thickened, compact layer of keratin with no retained nuclei.
Etymology
The term "Orthokeratosis" is derived from the Greek words "orthos" meaning straight or correct, and "keras" meaning horn. Thus, it can be translated as "correct horn formation", referring to the normal process of keratinization.
Related Terms
- Parakeratosis: A condition where the stratum corneum retains nuclei, which is abnormal and often associated with various skin diseases.
- Hyperkeratosis: An increase in the thickness of the stratum corneum, often seen in conditions like psoriasis and eczema.
- Keratinocyte: The primary cell type in the epidermis, responsible for the production of keratin.
- Keratin: A type of protein that makes up the majority of the stratum corneum, providing strength and resilience to the skin.
See Also
- Dermatology
- Histopathology
- Stratum corneum
- Epidermis
- Keratin
- Keratinocyte
- Parakeratosis
- Hyperkeratosis
External links
- Medical encyclopedia article on Orthokeratosis
- Wikipedia's article - Orthokeratosis
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