Monoclonal gammopathy

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Monoclonal gammopathy (pronunciation: /ˌmɒnəˈkləʊn(ə)l ˌɡæməˈpæθi/) is a condition characterized by the presence of an abnormal protein, known as a M protein or paraprotein, in the blood. It is produced by a clone of plasma cells, a type of white blood cell.

Etymology

The term "monoclonal gammopathy" is derived from the Greek words "monos" (meaning single), "klon" (meaning twig), and "gammopathy" (meaning disease of the gamma globulins).

Types

There are several types of monoclonal gammopathy, including:

Symptoms

Monoclonal gammopathy often does not cause symptoms. However, in some cases, it can lead to serious conditions such as kidney disease, nervous system disorders, and blood disorders.

Diagnosis

Monoclonal gammopathy is usually detected through a blood test called serum protein electrophoresis (SPEP). Other tests, such as immunofixation electrophoresis (IFE) and free light chain assay, may also be used.

Treatment

Treatment for monoclonal gammopathy depends on the type and severity of the condition. It may include chemotherapy, stem cell transplantation, or immunotherapy.

See also

External links

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