Passenger leukocyte

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Passenger Leukocyte

Passenger leukocyte (pronunciation: /ˈpasɪndʒər ˈljuːkəsaɪt/) is a term used in transplantation medicine to refer to the leukocytes or white blood cells that are transferred from the donor to the recipient during an organ transplant.

Etymology

The term "passenger leukocyte" is derived from the English words "passenger", meaning someone who travels in a vehicle, and "leukocyte", a term of Greek origin (leukos meaning "white", and kytos meaning "cell") referring to the white blood cells in the body.

Role in Transplantation

Passenger leukocytes play a significant role in the process of graft-versus-host disease (GVHD). These cells, which are part of the donor organ, can recognize the recipient's body as foreign and initiate an immune response, leading to GVHD.

Related Terms

  • Leukocytes: Also known as white blood cells, these are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
  • Transplantation (medicine): The process of transferring cells, tissues, or organs from one site to another, typically into another individual.
  • Graft-versus-host disease: A medical complication following the receipt of transplanted tissue from a genetically different individual.

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