Penetrance
| Penetrance | |
|---|---|
| Term | Penetrance |
| Short definition | penetrance - (pronounced) (PEH-neh trunks) Describes how likely it is that a person who has a specific disease-causing mutation (change) in a gene will show signs and symptoms of the disease. Not everyone who has the mutation will develop the disease. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
penetrance - (pronounced) (PEH-neh trunks) Describes how likely it is that a person who has a specific disease-causing mutation (change) in a gene will show signs and symptoms of the disease. Not everyone who has the mutation will develop the disease. For example, some people with a mutation in the BRCA1 or BRCA2 gene will develop cancer in their lifetime, while others will not. There is currently no way to know which people with a cancer-causing mutation will develop cancer. Complete penetrance means that any person who has the mutation will show signs and symptoms of the disease
External links
- Medical encyclopedia article on Penetrance
- Wikipedia's article - Penetrance
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