Pharmacometrics

Pharmacometrics (pronounced: far-muh-ko-meh-triks) is a field of study that focuses on the quantitative analysis of drug therapy, disease processes, and patient variability. It is a crucial aspect of Pharmacology and Clinical Pharmacology, providing a mathematical basis to describe and predict the behavior of drugs in the body.

Etymology

The term "Pharmacometrics" is derived from the Greek words "Pharmakon" meaning drug and "Metron" meaning measure. It essentially refers to the measurement of drug effects and their variability.

Definition

Pharmacometrics uses mathematical models to describe the relationship between drug dose and drug effect. It is a discipline that quantitatively analyzes the Pharmacokinetics (PK) and Pharmacodynamics (PD) of a drug. The goal of pharmacometrics is to improve the efficiency of Drug Development and regulatory decisions and to improve the labeling and dosage regimen in patient care.

Related Terms

Pharmacokinetics: The study of how a drug is absorbed, distributed, metabolized, and excreted by the body.
Pharmacodynamics: The study of the biochemical and physiological effects of drugs and their mechanisms of action.
Drug Development: The process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.
Clinical Pharmacology: The science of drugs and their clinical use. It is underpinned by the basic science of pharmacology, with added focus on the application of pharmacological principles and methods in the real world.
Pharmacology: The branch of medicine that deals with the uses, effects, and modes of action of drugs.

External links

Medical encyclopedia article on Pharmacometrics
Wikipedia's article - Pharmacometrics

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Pharmacometrics