Phenotype microarray
Phenotype Microarray
Phenotype Microarray (pronounced: fee-no-type my-cro-ar-ray) is a high-throughput method used in molecular biology to test the effect of thousands of conditions on the growth of a microorganism. The term is derived from the Greek words "phainein" (to show) and "typos" (type), and the English word "microarray".
Definition
A Phenotype Microarray is a type of Microarray that allows for the simultaneous analysis of thousands of phenotypes by monitoring the growth of a microorganism under different environmental conditions. This method is used to determine the metabolic and physiological properties of a microorganism.
Usage
Phenotype Microarrays are used in various fields of study, including Genetics, Microbiology, and Bioinformatics. They are particularly useful in the study of Genome function, as they can provide a comprehensive overview of the physiological and metabolic capabilities of an organism.
Procedure
The procedure for conducting a Phenotype Microarray involves inoculating a microorganism into a series of wells, each containing a different growth condition. The growth of the microorganism is then monitored over time, allowing for the determination of the organism's phenotype under each condition.
Related Terms
- Genotype: The genetic makeup of an organism, which can influence its phenotype.
- Microarray: A laboratory tool used to detect the expression of thousands of genes at once.
- Genome: The complete set of genes or genetic material present in a cell or organism.
- Bioinformatics: The science of collecting and analyzing complex biological data.
External links
- Medical encyclopedia article on Phenotype microarray
- Wikipedia's article - Phenotype microarray
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