From WikiMD
Jump to navigation Jump to search

The physiome of an individual's or species' physiological state is the description of its functional behavior. The physiome describes the physiological dynamics of the normal intact organism and is built upon information and structure (genome, proteome, and morphome). The term comes from "physio-" (nature) and "-ome" (as a whole).

In its broadest terms, it should define relationships from genome to organism and from functional behavior to gene regulation. In the context of the IUPS Physiome Project, it includes integrated models of components of organisms, such as particular organs or cell systems, biochemical, or endocrine systems.

The IUPS Physiome Project is a worldwide effort to define the physiome through the development of databases and models which will facilitate the understanding of the integrative function of cells, organs, and organisms. The project is focused on compiling and providing a central repository of databases, linking experimental information and computational models from many laboratories into a single, self-consistent framework. This coalescence of research effort will promote comprehensive databases and an integrative, analytical approach to the study of medicine and physiology.

The concept of a physiome project was presented to the International Union of Physiological Sciences (IUPS) by its Commission on Bioengineering in Physiology in 1993. A workshop on designing the Physiome Project was held in 1997. At its world congress in 2001, the IUPS designated the project as a major focus for the next decade.[1] The project is led by the Physiome Commission of the IUPS.[2]

Other research initiatives related to the physiome include:

See also


  1. Hunter, Peter J. (2003). "Integration from proteins to organs: the Physiome Project". Nature reviews. Molecular cell biology. 4 (3): pp. 237–243. doi:10.1038/nrm1054. PMID 12612642. Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: extra text (link)
  2. "Welcome to the NSR Physiome Project". NSR Physiome Project. last modified 28 October 2008. Retrieved 13 December 2008. Check date values in: |date= (help)

Portions of content adapted from Wikipedias article on Physiome licensed under GNU FDL.

External links

Exemplary physiome projects

W8MD logo250px


W8MD logo250px


W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP*

Quick links: Medicine Portal | Encyclopedia‏‎‏‎ | Gray's Anatomy‏‎ | Topics‏‎ |‏‎ Diseases‏‎ | Drugs | Wellness | Obesity‏‎ | Metabolic syndrome | Weight loss*
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer.
Link to this page: <a href="">Physiome</a>

  • Individual results may vary for weight loss from our sponsors.