Pickardt syndrome

Pickardt Syndrome

Pickardt Syndrome, also known as Pickardt-Fahlbusch Syndrome or Secondary Hypothyroidism with TSH Deficiency, is a rare medical condition characterized by the interruption of the hypothalamic-pituitary-thyroid axis. The pronunciation of the term is /pɪˈkɑːrdt ˈsɪndroʊm/.

Etymology

The syndrome is named after the German endocrinologist, Robert Pickardt, who first described the condition in 1975. The term "syndrome" is derived from the Greek word "σύνδρομον" (sýndromon), meaning "concurrence of symptoms".

Definition

Pickardt Syndrome is a form of secondary hypothyroidism, which is a condition where the thyroid gland is not the primary cause of decreased thyroid hormone production. In Pickardt Syndrome, the problem lies in the hypothalamus or the pituitary gland, which do not produce enough thyroid-stimulating hormone (TSH) to stimulate the thyroid gland to produce its hormones.

Symptoms

The symptoms of Pickardt Syndrome are similar to those of other forms of hypothyroidism and may include fatigue, weight gain, cold intolerance, constipation, and depression.

Diagnosis

Diagnosis of Pickardt Syndrome is based on a combination of clinical findings, laboratory tests showing low levels of thyroid hormones (T3 and T4) and TSH, and imaging studies of the hypothalamus and pituitary gland.

Treatment

Treatment for Pickardt Syndrome typically involves hormone replacement therapy to restore normal thyroid hormone levels.

Related Terms

External links

Medical encyclopedia article on Pickardt syndrome
Wikipedia's article - Pickardt syndrome

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Pickardt syndrome