Plecanatide
Plecanatide
Plecanatide (pronounced plek-uh-nuh-tide) is a medication used in the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). It is marketed under the brand name Trulance.
Etymology
The name "Plecanatide" is derived from the peptide on which it is based, known as guanylin. The "plec" part of the name is an arbitrary prefix, while the "anatide" suffix is common in drugs that are peptides or based on peptides.
Pharmacology
Plecanatide is a guanylate cyclase-C (GC-C) agonist. It works by increasing the amount of fluid in the gastrointestinal tract, which can help to ease the passage of stool and reduce symptoms of constipation.
Usage
Plecanatide is used to treat chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). It is taken orally, usually once a day.
Side Effects
Common side effects of Plecanatide include diarrhea, stomach pain, gas, heartburn, vomiting, and fatigue. If these side effects persist or worsen, patients are advised to contact their healthcare provider.
Related Terms
External links
- Medical encyclopedia article on Plecanatide
- Wikipedia's article - Plecanatide
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