Solitary fibrous tumor
Solitary Fibrous Tumor
Solitary fibrous tumor (pronunciation: so-luh-ter-ee fi-brus too-mer) is a rare type of tumor that originates from the mesenchyme, the embryonic connective tissue. The term "solitary" refers to the fact that these tumors typically occur as a single, well-defined mass, while "fibrous" describes the tumor's composition of spindle-shaped cells in a patternless or storiform pattern.
Etymology
The term "solitary fibrous tumor" was first used in 1931 by Klemperer and Rabin, who described the tumor as a distinct entity separate from mesothelioma. The term "solitary" is derived from the Latin word "solus", meaning "alone", and "fibrous" from the Latin "fibra", meaning "fiber". This reflects the tumor's typical presentation as a single, fibrous mass.
Related Terms
- Fibroma: A benign tumor composed of fibrous or connective tissue.
- Sarcoma: A type of cancer that originates from connective tissues, such as bones, muscles, fat, and blood vessels.
- Hemangiopericytoma: A rare type of tumor that was once thought to be related to solitary fibrous tumors, but is now considered a separate entity.
- Pleura: The membrane that surrounds the lungs and lines the chest cavity. Solitary fibrous tumors can originate from the pleura.
Diagnosis
Diagnosis of a solitary fibrous tumor often involves a combination of imaging studies, such as CT scan or MRI, and biopsy to examine the tissue under a microscope. The tumor is often positive for CD34, a protein that is expressed on the surface of certain types of cells.
Treatment
Treatment for solitary fibrous tumors typically involves surgical removal of the tumor. In some cases, radiation therapy or chemotherapy may be used, particularly if the tumor is malignant or cannot be completely removed with surgery.
Prognosis
The prognosis for solitary fibrous tumors varies widely and depends on factors such as the size and location of the tumor, whether it is benign or malignant, and whether it can be completely removed with surgery.
External links
- Medical encyclopedia article on Solitary fibrous tumor
- Wikipedia's article - Solitary fibrous tumor
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