Podophyllotoxin

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Podophyllotoxin

Podophyllotoxin (pronunciation: /ˌpoʊdoʊfɪˈlɒtɒksɪn/) is a non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species.

Etymology

The term "Podophyllotoxin" is derived from the Greek words 'pous' meaning foot, 'phyllon' meaning leaf, and 'toxikon' meaning poison. This refers to the plant's foot-like leaves and its toxic properties.

Description

Podophyllotoxin is a cytotoxic compound that has been used in the production of several chemotherapeutic drugs. It is used primarily in the treatment of certain types of cancer, including testicular cancer and small cell lung cancer. It works by inhibiting the growth of cancer cells and eventually killing them.

Related Terms

  • Podophyllin: A resinous mixture, used topically in the treatment of genital warts. It contains a number of compounds, including podophyllotoxin.
  • Etoposide: A semisynthetic derivative of podophyllotoxin used in the treatment of various types of cancers.
  • Teniposide: Another semisynthetic derivative of podophyllotoxin, used to treat certain types of leukemia.

See Also

External links

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