Polyvinylpolypyrrolidone

Polyvinylpolypyrrolidone (pronunciation: pol-ee-vin-yl-pol-ee-pi-rol-i-done), also known as PVPP or Crospovidone, is a highly cross-linked modification of Polyvinylpyrrolidone (PVP). It is a synthetic polymer that is widely used in the pharmaceutical industry as a disintegrant, a substance that promotes the breakup of a tablet in the digestive tract after ingestion.

Etymology

The term "Polyvinylpolypyrrolidone" is derived from its chemical structure. It is a polymer (poly-) of vinyl (-vinyl-) and pyrrolidone (-pyrrolidone) units. The prefix cross- in Crospovidone refers to the cross-linking of the polymer chains.

Usage

Polyvinylpolypyrrolidone is primarily used in the pharmaceutical industry. It is a common ingredient in tablets and capsules, where it acts as a disintegrant. Disintegrants ensure that the tablet or capsule disintegrates into smaller fragments in the stomach, allowing the active ingredient to be released and absorbed by the body.

In addition to its role as a disintegrant, Polyvinylpolypyrrolidone also has applications in the food and beverage industry. It is used as a stabilizer in beer and wine, where it binds to and removes polyphenols that can cause haze and affect the taste of the product.

Related Terms

Polyvinylpyrrolidone: A water-soluble polymer used as a binder in pharmaceutical tablets and as a complexing agent in cosmetics.
Disintegrant: A substance added to a pharmaceutical dosage form such as a tablet, capsule, or granule to promote its breakup after administration.
Polyphenols: A type of chemical that occurs naturally in many plants. Polyphenols have antioxidant properties and are the focus of many studies on health and nutrition.

External links

Medical encyclopedia article on Polyvinylpolypyrrolidone
Wikipedia's article - Polyvinylpolypyrrolidone

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Polyvinylpolypyrrolidone