Preclinical research

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Preclinical Research

Preclinical research (pronunciation: pre-klin-i-kal ree-surch), also known as preclinical study or nonclinical study, refers to laboratory experiments conducted on cells, animals, and animal models before they are performed on humans. This phase of research helps to identify the safety and efficacy of a treatment or therapeutic intervention before it is tested in clinical trials.

Etymology

The term "preclinical" is derived from the prefix "pre-", meaning "before", and "clinical", which refers to the observation and treatment of actual patients. "Research" originates from the Old French "recherche", which means "to seek out or search closely". Thus, "preclinical research" essentially means "research before clinical trials".

Related Terms

  • Clinical Trials: These are research studies performed on humans to evaluate the safety and effectiveness of a medical, surgical, or behavioral intervention.
  • In Vitro: This term refers to studies conducted in a controlled environment, such as a test tube or petri dish, outside of a living organism.
  • In Vivo: In contrast to in vitro, in vivo studies are conducted in living organisms.
  • Pharmacodynamics: This is the study of the biochemical and physiological effects of drugs on the body.
  • Pharmacokinetics: This refers to how the body absorbs, distributes, metabolizes, and excretes drugs.
  • Toxicology: This is the study of the adverse effects of chemical substances on living organisms.

See Also

External links

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