Information about Prednisone
Prednisone (pred' ni sone) is a synthetic, intermediate acting glucocorticoid that is widely used in the therapy of severe inflammation, autoimmune conditions, hypersensitivity reactions and organ rejection.
Mechanism of action of Prednisone
Prednisone is converted to prednisolone, its active form, in the liver.
Dosage and administration for Prednisone
Prednisone is available in multiple generic forms in tablets of 1, 2.5, 5, 10, 20 and 50 mg and as oral solutions.
Clinical use of Prednisone
Four times more potent that cortisol, prednisone is used in varying doses, with 5 mg daily being considered physiologic doses in adults.