Progressive familial intrahepatic cholestasis
| Progressive familial intrahepatic cholestasis | |
|---|---|
| Term | Progressive familial intrahepatic cholestasis |
| Short definition | progressive familial intrahepatic cholestasis - (pronounced) (pruh-GREH-siv fuh-MIH-lee-ul IN-truh-heh-PA-tik koh-leh-STAY-sis) rare inherited disorder characterized by a buildup of bile (fluid that helps digest fat) in the liver. This can lead to liver disease and liver failure. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
progressive familial intrahepatic cholestasis - (pronounced) (pruh-GREH-siv fuh-MIH-lee-ul IN-truh-heh-PA-tik koh-leh-STAY-sis) rare inherited disorder characterized by a buildup of bile (fluid that helps digest fat) in the liver. This can lead to liver disease and liver failure. It can also increase the risk of liver cancer. Progressive familial intrahepatic cholestasis is caused by mutations (changes) in certain genes that make proteins needed for the liver to function as it should. It usually occurs in infants and children. Also called PFIC
External links
- Medical encyclopedia article on Progressive familial intrahepatic cholestasis
- Wikipedia's article - Progressive familial intrahepatic cholestasis
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